AOPEP and familial hypercholesterolemia: In fact, in studies where high oleic sunflower oil was replaced with palm olein in postmenopausal women, as noted above, the most important differences in the oxidized LDL, APO A2 and APO A1/APO A2 ratios were found in women with hypercholesterolemia, with no major differences in other markers between normo- and hypercholesterolemia.