In this study,the NSE level in patient with paraplegia was at the upper limit throughout theprocedure and this did not change significantly during the entire procedure,however this was non-specific as the same increase was noted in patients who didnot develop any evidence of SCI, on the contrary, it was noted that one of thepatients who developed stroke postoperatively had a high level of serum NSEwhich peaked at first postoperative day. This evidence concerns the gene ENO2 and Stroke.