Blood levels of adipokines (leptin, soluble leptin receptor, and high molecular weight adiponectin) were measured by enzyme-linked immunosorbent assay and were compared relative to BMI ≥25 kg/m2 and to none, ≤1 component or ≥2 components of the metabolic syndrome (waist circumference, blood pressure, fasting glucose, low levels of high-density lipoproteins, and triglycerides).80 Epicardial and pericardial fat increased while hepatic fat decreased with increasing BMI and components of the metabolic syndrome. This evidence concerns the gene LEPR and metabolic syndrome.