P2RX7 and age-related macular degeneration: Retinal cells (human retinal pigment epithelial ARPE-19 cell line and human retinal Müller glial MIO-M1 cell line) were incubated with amyloid β peptide or oxysterols, involved in degenerative diseases such as Alzheimer and age-related macular degeneration, then the YO-PRO-1 assay that we describe here was used to study P2X7 receptor activation.