Indeed, in PNH and aplastic anemia, in addition to JAK2, TET2 and HMGA2 (mentioned above), mutations in ASXL1, DNMT3a, BCOR, BCORL1, SUZ12, and U2AF1 have been reported [39–41]. The gene discussed is TET2; the disease is paroxysmal nocturnal hemoglobinuria.