At both 2 and 12 weeks p.i., the largest proportional increase driven by PIK3CAH1047R expression is seen in NKX2-1+/SFTPA- tumor cells (Figure 4G–H), implying that at both early and late time points, decreased expression of NKX2-1 cannot explain the observed decrease in SFTPA expression. This evidence concerns the gene NKX2-1 and neoplasm.