To date, FZD4(MIM, 604579, AD), LRP5(MIM 603506, AD, or AR), TSPAN12(MIM 613138, AD), KIF11(MIM 148760, AD), NDP(MIM 300658, XLR), ZNF408(MIM 616454, AD) have been implicated in FEVR (Deng et al., 2013; Prasov et al., 2012; Rao et al., 2017). This evidence concerns the gene LRP5 and Alzheimer disease.