PTEN and neoplasm: miR-17-5p, -19a-3p, -19b-3p, -21-5p, -130b-3p, -221-3p, and -222-3p have been found overexpressed in GSCs and correlated with reduced expression of their common target Phosphatase and Tensin Homolog (PTEN), leading to anti-apoptotic effects, promoting tumor growth, and sustaining a stem-cell-like phenotype [89,90].