We further observed that ALDOC significantly lowered mRNA expression in the glioblastoma compared with the non-tumor part, the non G-CIMP compared with the G-CIMP group, and unmethylated MGMT compared with MGMT methylated patients (p < 0.0001, p = 0.0019, and p = 0.0356, respectively) (Figure 1C). The gene discussed is MGMT; the disease is neoplasm.