Through established transcriptomics data sets, proteomics, and metabolomics between parental or IDH1 R132 mutant in U-87 cells, combined with our available microarray data sets from ALDOC knockdown models, we expected to find the interaction partners, signaling pathways, or metabolites by ALDOC regulated in only wild-type or R132 mutant of IDH1 in GBM. This evidence concerns the gene IDH1 and glioblastoma.