Our results add to the growing body of knowledge of sortilins as proteins that affect processing of antigens in autoimmunity and other functions related to the immune system by providing evidence that gene expression or genetic diversity of sortilin and MHC/HLA genes are associated with mHTT in HD (Figure 1, Figure 2, Figure 3 and Figure 5; Supplementary Materials Table S3). This evidence concerns the gene HLA-C and Autoimmunity.