In both datasets, a continuous haplotype block including SNP Chr1:109950858 (indicated in the red square in Figure 5), upstream of SORT1 is in association with another haplotype block in region Chr4:3236883-3238643 near HTT in HD cases, but not in controls of both Labadorf and Lin datasets (Figure 5, Supplementary Materials Figure S4). The gene discussed is SORT1; the disease is Huntington disease.