This is the first study that measured serum levels of pro-inflammatory interleukins IL-1-α, IL-1β, IL-2, IL-4, IL-6, IL-8, interferon-γ (IFN-γ),TNF-α, monocyte chemoattractant protein 1 (MCP-1), the anti-inflammatory interleukin IL-10 and growth factors, such as vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) in individuals with depressive and EDs comorbidity and dysfunctional eating behaviors at opposite ends of the BMI range. This evidence concerns the gene IL1B and Ehlers-Danlos syndrome.