Strong immunoreactivity to metastatic marker, Slug/Snail, mesenchymal markers, Vimentin and N-cadherin, epithelial marker, E-cadherin, and proliferative marker Ki67 was found in immunohistochemical observation of the metastatic tumor in liver compared to the primary tumor in spleen. The gene discussed is MKI67; the disease is metastatic neoplasm.