SELENBP1 and brain ischemia: Patients suffering from bradycardia, death, or cerebral ischemia (combined endpoint 1) displayed markedly elevated serum concentrations of SELENBP1 at several points compared to those patients without any of these serious events (p = 0.033 at 45 min after induction of ischemia, p = 0.0051 at 2 min after reperfusion, p = 0.0011 at 15 min after weaning from the CPB, and p = 0.0017 at 1 h after arrival on the ICU) (Figure 6).