To indirectly determine whether observed methylation changes affect the expression of proximal genes, for the five probes (cg12169243 in DPH6; cg25429010 in IMP3; cg25021476 in RSL24D1; cg04989085 in FAM113B; and cg20905681 in CKAP4), we analyzed the correlation between methylation and expression (RNA sequencing) using The Cancer Genome Atlas (TCGA, http://cancergenome.nih.gov/) data. The gene discussed is CKAP4; the disease is cancer.