From the association analysis of patients with advanced-stage NSCLC (stages IIIb and IV, n = 67) versus those with stage I disease (n = 46), we identified 58 suggestive DMPs and four significant DMPs (cg25021476 [RSL24D1], cg04989085 [FAM113B], cg20905681 [CKAP4], and cg26379694) (Table 4). This evidence concerns the gene CKAP4 and non-small cell lung carcinoma.