IL1B and infection: For instance, EBOV in vitro infection of monocytes and macrophages triggers the robust expression of inflammatory mediators, including IL-1β, IL-6, IL-8, MIP-1a, MIP-1β, MCP-1, and TNF-α [15,16], whereas the dysregulation of immune mediators in humans has been associated with the secretion of other inflammatory mediators, such as IL-1β, IL-8, CCL2, CCL3, CCL13, CXCL1, CXCL10, CXCL11, CXCL12, IL6, MIF, SPP [17,18,19].