These products (eg, insulin‐like growth factor and leptin) are related to malignancies, probably via inducing pro‐growth changes in the cycle of a cell, declined cell death, and pro‐neoplastic cellular variations.20 Meta‐analysis showed that risen BMI correlated with the CGA risk (CGA, summary relative risk, SRRs = 1.21 and 1.82 for overweight and obesity, respectively, but not with NCGA (NCGA; SRRs = 0.93 and 1.00 for overweight and obesity, respectively.21 A meta‐analysis revealed a 21% decline in GC risk, in those having higher physical activity compared to the least active ones. This evidence concerns the gene LEP and obesity due to melanocortin 4 receptor deficiency.