The results of the enrichment analysis indicated that the miR‐181a targets were enriched for miRNAs in cancer, FoxO, pathways in cancer, proteoglycans in cancer, colorectal cancer, PI3K‐Akt, and VEGF pathway while the miR‐181b targets were enriched for FoxO, HIF‐1, miRNAs in cancer, PI3K‐Akt, pathways in cancer, mTOR, colorectal cancer, central carbon metabolism in cancer, Proteoglycans in cancer, and cAMP pathway. This evidence concerns the gene MTOR and cancer.