ZEB1 and neoplasm: The transcription of miR-141 and miR-200c might be directly suppressed by ZEB1, which could strongly activate epithelial differentiation of pancreatic, colorectal and breast cancer cells (30, 31).The ectopic expression of miR-93 might promote cell proliferation, migration, invasion, EMT and formation of tumor while it inhibited cell apoptosis and G1 cell cycle arrest (32).