In lung adenocarcinoma, 18 genes (SLCO1A2, PYROXD1, RECQL, LDHB, CMAS, KIAA0528, ETNK1, ASUN, FGFR1OP2, TM7SF3, MED21, MRPS35, KLHDC5, CCDC91, FGD4, DNM1L, YASR2, and KRAS) in 12p12.1 were found to have increased copy number and coamplified with KRAS, 88.9% (8/9) genes in our study were included. The gene discussed is LDHB; the disease is lung adenocarcinoma.