Moreover, HbA1c, CTGF, UACR, and miR-154-5p levels in the post-menopausal female T2DM patients increased successively in the F1-3 groups while the levels of ADPN, P1NP, β-CTx, and OC were reduced (P < 0.05, Table 3 and Figure 1C). This evidence concerns the gene CCN2 and type 2 diabetes mellitus.