CSF1R and acute kidney injury: A number of studies respectively pinpointed the role of M1 and M2 Mφ using various Mφ depletion strategies during and after the induction of AKI, including: (1) systemic administration of Mφ-depleting clodronate or (2) neutralizing CSF-1R antibody; and (3) DT injection in mice expressing DTR on Mφ.