CFL2 and Alzheimer disease: The ELISA results showed that AD patients presented higher serum levels of cofilin 2 in comparison to the controls, and cofilin 2 in MCI group was significantly higher than the control group and significantly lower than the AD group (AD: 167.9 ± 35.3 pg/ml, MCI: 115.9 ± 15.4 pg/ml, Control: 90.5 ± 27.1 pg/ml, p < 0.01).