Numerous cytokines, e.g., tumor necrosis factor (TNF) (Irene et al., 2015), interleukin-1 (IL-1) (Irene et al., 2015), interleukin-6 (IL-6) (Haddick et al., 2017), and colony-stimulating factor (CSF) (Vincent et al., 2009), have been suggested to be connected with the course of AD. The gene discussed is TNF; the disease is Alzheimer disease.