While monotherapy with anti-PD-L1 mAb presented a marginal effect on sustaining Db/I-tetramer+ TCR-I CD8 T cells in the dLN, tumor, or spleen, B10G5 therapy consistently sustained the adoptively transferred TCR-I CD8 T cells with high frequency in the tumor as we have previously shown [28] (Fig. 3b, c). This evidence concerns the gene CD8A and neoplasm.