LPL and Insulin resistance: Genetically raised LPL levels were associated with increased risk of type 2 diabetes (OR per SD unit increase, 1.10; 95% CI 1.06, 1.15; p = 6.7 × 10−7), with a directionally consistent but statistically weak effect on insulin resistance (change in natural log-scaled HOMA-IR per SD unit, 0.02; 95% CI 0.00, 0.04; p = 0.046, ESM Table 5).