TNFSF10 and pancreatic neoplasm: Ge et al. demonstrated that an oncolytic adenoviruscoexpressing TRAIL and Smac, in combination with the cyclin-dependent kinase(CDK) inhibitor SNS-032, synergistically reinforced their individualanti-pancreatic cancer activities, and SNS-032 enhancedZD55-TRAIL-IETD-Smac-induced apoptosis [131].