ZNF292 and Miyoshi myopathy: Genes with rather more mysterious function were also significant: the zinc finger ZNF292, recently described as mutated in MM, chronic lymphocytic leukemia and diffuse large B-cell lymphoma13,20,21, showed an excess of protein-truncating variants (Supplementary Fig. 2h); the uncharacterized TBC1D29 gene showed missense mutations clustered in the last exon22 (Supplementary Fig. 2i).