Likewise, no prognostic significance was found for PLR and AGR in the IDH and TERT mutation group (Supplementary Figure 1E, 1F), MLR and AGR in the IDH mutation only group (Supplementary Figure 1G, 1H), MLR and AGR in the TERT mutation only group (Supplementary Figure 2A, 2B), and PLR, MLR, and AGR in the triple-negative group (Supplementary Figure 2C–2E) of lower-grade gliomas. This evidence concerns the gene IDH1 and central nervous system cancer.