IDH2 and central nervous system cancer: As shown in Figure 2F–2L, univariate analysis showed that high NLR predicted shorter OS in lower-grade glioma groups defined by IDH and TERT mutations (P = 0.009), IDH mutation only (P = 0.047), TERT mutation only (P = 0.005), and in the triple-negative group (P = 0.005).