Inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins 1, 6 and 8 (IL-1/6/8) may interfere with the function of natural killer cells, cytotoxic T-lymphocytes, and antigen-presenting cells [21–23], which promote the growth and metastasis of tumor cells. Here, TNF is linked to neoplasm.