Both nonpreconditioned and EPA-preconditioned AD-MSCs were able to reduce TGF-β levels, interstitial edema, and collagen fiber content in the lung; however, EPA-preconditioned AD-MSCs were more effective at reducing alveolar collapse, interstitial edema, and lung fibrosis, while also increasing VEGF levels in lung tissue. Here, TGFB1 is linked to pulmonary fibrosis.