IL10 and Alzheimer disease: Although EPA preconditioning did not affect AD-MSC morphology, surface markers, in vitro survival, or in vivo biodistribution in the present study, we observed that EPA actively increased secretion of anti-inflammatory and pro-resolution mediators by AD-MSCs, including resolvin D1, PGE2, IL-10, and TGF-β, as in a previous study by our group that used bone marrow-derived MSCs in allergic asthma [17].