Though CTA-384D8.35, CTB-114C7.4 and miR-4497 have not been studied yet, their functions could be interpreted by their target genes in the ceRNA network, including inflammatory responses (CCL3 [50], ZFP36 [51], IER3 [52]), apoptosis (EGR1) [53], atherosclerosis and myocardial ischemia (FOS) [54]. The gene discussed is IER3; the disease is atherosclerosis.