Studies have shown the abnormal expression of micro RNA (miRNA) and long non-coding RNA (lncRNA) in CVD, including miR-1, miR-208, miR-499 in myocardial infarction [9–12], miR-126 in hyperlipidemia [13] and cardiovascular events [14], lncRNA ANRIL, KCNQ1OT1, MIAT, and MALAT1 in left ventricular dysfunction after myocardial infarction [15, 16], and lncRNA OTTHUMT00000387022 as novel biomarker for coronary heart diseases [17]. The gene discussed is KCNQ1OT1; the disease is myocardial infarction.