By double immunofluorescence staining on SKOV3/NOD SCID xenograft ovarian model and human ovarian carcinoma tissues (Figure 3), we analyzed the expression of either SDC1 or B-FN with vascular markers, including CD31, smooth muscle actin (SMA), and Desmin; VM markers, including VEGFR2 and VE-cad; and ovarian cancer stem cell markers, such as EpCAM, CD44, and CD133/1. This evidence concerns the gene DES and ovarian cancer.