PPARGC1A and hydrops fetalis: Similar to phosphorylated AMPKα2, maternal or post-weaning HF diet significantly decreased PGC-1α expression in the HF/ND group (112 ± 14 positive cells) and the ND/HF group (121 ± 21 positive cells) vs. the ND/ND group (220 ± 29 positive cells) (Figure 4A).