CCL2 and hydrops fetalis: In the distal gut (ileum), HF feeding was associated with significant upregulation in gene expression of macrophage infiltration markers, CD68 (HF vs. LF, p < 0.01) and MCP1 (HF vs. LF, p < 0.001), which was normalized by probiotic supplementation (HF/Pro) and partially normalized in the encapsulated group (HF/Pca) (CD68, HF vs. HF/Pro, p < 0.01; HF vs. HF/Pca, p < 0.05; MCP1, HF vs. HF/Pro, p < 0.01; HF vs. HF/Pca, ns; Figure 5B).