Increased expression of pluripotency transcription factors Sox2, Oct4, Nanog, Klf4, Hes1, receptor Lgr5, surface marker molecules CD24, CD26, CD44, CD133, CD166, isoforms of aldehyde dehydrogenase (ALDH), and ATP binding cassette subfamily G member 2 (ABCG2) was detected in cisplatin-resistant cell line variants derived from lung adenocarcinoma, malignant pleural mesothelioma and non-small cell lung cancer cells [12,13,14]. Here, CD44 is linked to malignant pleural mesothelioma.