In 1161 RCC patients who underwent surgery, multivariate analysis revealed that CRP level is an independent prognosticator for cancer-specific survival (HR = 1.007, 95% CI = 1.004–1.009, p < 0.001) as well as OS (HR = 1.006, 95% CI = 1.004–1.008, p < 0.001) [128]. Here, CRP is linked to cancer.