NR4A1 and neoplasm: In a multivariate model including pre-chemotherapy tumor size, nodal status, grading, hormone receptor status, C4M levels at baseline and changes in C4M levels between baseline and after four cycles of therapy, only C4M levels at baseline (p = 0.028, OR 6.203, 95%-CI 1.220–31.546) and tumor size (p = 0.035, OR 4.900, 95%–CI 1.122–21.393) were independent predictors of pCR.