We used combinations of the following search terms: “neuroketotherapeutic”, “ketone”, “fasting”, “ketogenic diet”, “medium chain triglyceride”, “MCT”, “exogenous ketone”, “ketone monoester”, “ketone diester”, “beta-hydroxybutyrate”, “BHB”, “acetoacetate”, “AcAc”, “coconut oil”, “Alzheimer disease”, “mild cognitive impairment”, “amyloid”, and “tau.” In order to identify ongoing clinical trials and potentially unreported or negative clinical trials, we also searched www.clinicaltrials.gov using the same search terms. Here, MAPT is linked to Alzheimer disease.