DNM1L and myocardial infarction: Although pharmacological inhibition of the mitochondrial fission protein, Drp1, using either mdivi-1 or P110 at the onset of reperfusion has been reported to reduce MI size in rodent AMI models, in our pilot study we did not find any cardioprotective effect with mdivi-1 (at a dose of 1.2 mg/kg) administered as a single intracoronary bolus in a clinically-relevant pig AMI model.