Here, the new biomarkers that were found in the VEGF signaling included phosphorylations of CAV1 at residue S6 (fold change = 0.03, p = 8.07E-07), CAV1 at residue S26 (fold change = 0.06, p = 9.35E-09), CTNNA1 at residue S518 (fold change = 0.78, p = 1.00E-04), HSP90 at residue S217 (fold change = 0.80, p =2.83E-02), CFL1 at residue S3 (fold change = 0.29, p = 8.00E-05), and MYH9 at residue S1943 (fold change = 1.40, p = 7.70E-03), which might be novel molecules and regulation mechanism for tumor angiogenesis. The gene discussed is HSP90AA1; the disease is neoplasm.