EIF2AK3 and Wolcott-Rallison syndrome: In consanguineous families with high level of homozygosity, PNDM is commonly associated with syndromic forms of DM, with recessive eukaryotic translation initiation factor 2‐alpha kinase 3 (EIF2AK3) mutations causing Wolcott–Rallison Syndrome (WRS) (OMIM 226980) being the most frequent cause (Habeb et al., 2012; Rubio‐Cabezas & Ellard, 2013).