IKBKB and neoplasm: For example, misexpression of IκB that was used to inhibit NF‐κB activity reduced denervation‐induced muscle wasting in tumour‐bearing mice.52 Denervation‐induced atrophy was also attenuated in mice lacking IKKβ.53 Inhibition of NF‐κB by BMS‐3445541 could therefore be useful to prevent denervation‐induced muscle wasting as well.