Sepsis led to a decreased Myh4 expression (sham + vehicle vs. CLP + vehicle: −56%, P < 0.01; sham + BMS‐345541 vs. CLP + BMS‐345541: −15%, n.s.), which was attenuated by 34% by BMS‐345541 (P < 0.05). This evidence concerns the gene MYH4 and Sepsis.