The oncogenic role of SNHG16 was identified in several types of cancers including hepatocellular carcinoma,16 glioma,24 osteosarcoma,18 bladder cancer 25 and cervical cancer.17 Among these cancers, SNHG16 promoted the cancer cell proliferation and migration via distinct molecular mechanisms. The gene discussed is SNHG16; the disease is hepatocellular carcinoma.