TRPM4 contributes to migration in multiple cellular systems, including immune cells, vascular endothelial cells, and PCa cells (Barbet et al., 2008; Holzmann et al., 2015; Sagredo et al., 2019; Sarmiento et al., 2015; Shimizu et al., 2009). The gene discussed is TRPM4; the disease is posterior cortical atrophy.