Transient receptor potential melastatin‐4 channel (TRPM4) is expressed in several human tissues (Launay et al., 2002; Nilius et al., 2003) and has been identified as a cancer driver gene that contributes to migration, proliferation, and invasion of prostate cancer (PCa) cells (Berg et al., 2016; Holzmann et al., 2015; Sagredo et al., 2018, 2019; Schinke et al., 2014). This evidence concerns the gene TRPM4 and Familial prostate cancer.