ANXA5 and colonic neoplasm: More than 90% of cells treated with a high dose (0.9% v/v) of flaxseed oil for 3 days bound annexin V. This is consistent with other studies that have shown increased annexin V binding in cultured breast, prostate, or colon cancer cells treated with flaxseed oil or α-linolenic acid [17, 25, 30, 31].