ELAVL1 regulates numerous mRNAs that encode proteins related to proliferation, cell cycle (cyclins A2, B1, D1, p21, and p27), tumor suppressors (p53 and Von Hippel-Lindau tumor suppressor), proto-oncogene products (c-Fos and c-Myc), growth factors (IGF-1R VEGF, EGF, TGF, GM-CSF), inhibitors (p21 and p27) and signaling molecules, which are crucial (β-catenin, cyclin D1, and c-Myc) for the CRC WNT-activated pathway (Lin et al., 2017). The gene discussed is VEGFA; the disease is colorectal carcinoma.