CXCL10 and infection: In order to assess whether CXCL10 cleavage is occurring intracellularly or extracellularly during infection, we harvested THP-1 monocytes at 24 h post-infection with either L. major WT, Δgp63, or Δgp63+1, counted the number of living cells, and measured CXCL10 in both the supernatants and cell lysates.