CXCR3 and infection: Specifically, transcription of Cxcl10 is upregulated in T resident-memory (Trm) cells after secondary infection, and antibody blockade of CXCR3 prevents recruitment of circulating CD4+ T cells to the site of infection (Glennie et al., 2015; Glennie and Scott, 2016; Romano et al., 2017).