CXCL10 and infection: After infection with lymphocytic choriomeningitis virus, CXCR3 deletion leads to impaired production and localization of effector CD8+ T cells (Hu et al., 2011), and CXCL10 precisely coordinates effector CD8+ T cells to the site of Toxoplasma gondii, another intracellular eukaryotic pathogen (Harris et al., 2012).