AFP and hepatocellular carcinoma: As shown in Table 2, the multivariate logistic regression analysis revealed that younger age (P = 0.001), non-white race (P < 0.001), higher T stage (P < 0.001), higher N stage (P < 0.001), larger primary tumor size (P < 0.001), elevated AFP (P < 0.001), and presence of bone (P < 0.001), brain (P < 0.001), and intrahepatic metastasis (P < 0.001) were the potential significant predictors for PM from HCC.