This phenomenon is consistent with previous studies, which reported that increased μ-calpain and m-calpain expression were observed in numerous cancers, such as schwannomas, meningiomas, colorectal adenocarcinomas, and breast cancer (Kimura et al., 1998; Lakshmikuttyamma et al., 2004; Storr et al., 2011; Storr et al., 2012). This evidence concerns the gene CAPN2 and colorectal adenocarcinoma.