ITGB6 and familial dilated cardiomyopathy: The ITGB6 gene, which encodes a protein of the integrin superfamily, is involved in all of the DCM, HCM, and ARVC pathways, and it has been reported to be particularly closely related to the ARVC pathway (O’Leary et al., 2015; Stelzer et al., 2016).